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IM-12
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IM-12图片
CAS NO:1129669-05-1
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
10mM * 1mL in DMSO电议

产品名称
IM12, IM 12
产品介绍

生物活性

IM-12是一种细胞渗透性吲哚标记,作为糖原合成酶激酶3β(GSK-3β)抑制剂,激活典型Wnt信号的下游成分。

靶点信息

GSK-3β
53 nM

化学数据

目录号A14196
作用机制Inhibitor (抑制剂)
M. Wt377.41
FormulaC22H20FN3O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1129669-05-1
SynonymsIM12, IM 12
SMILESCC1=C(C2=CC=CC=C2N1)C3=C(C(=O)N(C3=O)C)NCCC4=CC=C(C=C4)F

溶解度

In vitroDMSO72 mg/mL (190.77 mM)
WaterInsoluble
EthanolWarmed: 10 mg/mL (26.49 mM)
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.5 mL132.48 mL264.96 mL
0.5 mM5.3 mL26.5 mL52.99 mL
1 mM2.65 mL13.25 mL26.5 mL
5 mM0.53 mL2.65 mL5.3 mL

*The above data is based on the productmolecular weight 377.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.