生物活性
Abacavir是一种核苷类似物逆转录酶抑制剂（NRTI）；鸟苷类似物用于治疗艾滋病毒和艾滋病。
化学数据
| 目录号 | A11115 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 286.3 |
| Formula | C14H18N6O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 136470-78-5 |
| SMILES | C1CC1NC2=NC(=NC3=C2N=CN3[C@@H]4C[C@@H](C=C4)CO)N |
溶解度
| In vitro | DMSO | 55 mg/mL (192.09 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 34.93 mL | 174.64 mL | 349.28 mL |
| 0.5 mM | 6.99 mL | 34.93 mL | 69.86 mL |
| 1 mM | 3.49 mL | 17.46 mL | 34.93 mL |
| 5 mM | 0.7 mL | 3.49 mL | 6.99 mL |
*The above data is based on the productmolecular weight 286.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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