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YM155(Sepantronium Bromide)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
YM155(Sepantronium Bromide)图片
CAS NO:781661-94-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
100mg电议
10mM * 1mL in DMSO电议

产品介绍

生物活性

YM155 (Sepantronium Bromide)是一种新型小分子存活蛋白抑制剂,IC50为0.54 nM,可抑制存活蛋白启动子活性。

靶点信息

Survivin (HeLa-SURP-luc, CHO-SV40-luc cells)
0.54 nM

化学数据

目录号A11002
作用机制Inhibitor (抑制剂)
M. Wt443.3
FormulaC20H19BrN4O3
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.781661-94-7
SMILESCC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]

溶解度

In vitro (25°C)DMSO52 mg/mL (117.3 mM)
Water85 mg/mL (191.75 mM)
Ethanol6 mg/mL (13.53 mM)
In vivoSaline28 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.56 mL112.79 mL225.58 mL
0.5 mM4.51 mL22.56 mL45.12 mL
1 mM2.26 mL11.28 mL22.56 mL
5 mM0.45 mL2.26 mL4.51 mL

*The above data is based on the productmolecular weight 443.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.