Background:

U91356 is a dopamine receptor agonist.

U91356 (U-91356) shows good dopaminergic agonist activity, and has good metabolic stability and oral bioavailability in the rat and monkey[2].

[1]. Kreiss DS, et al. Dopamine receptor agonist potencies for inhibition of cell firing correlate with dopamine D3receptor binding affinities. Eur J Pharmacol. 1995 Apr 24;277(2-3):209-14. [2]. Moon MW, et al. Medicinal chemistry of imidazoquinolinone dopamine receptor agonists. Drug Des Discov. 1993;9(3-4):313-22.