生物活性
Vanoxerine 2HCl (GBR-12909)是哌嗪衍生物，是一种有效的、选择性的多巴胺摄取（dopamine uptake）抑制剂。
化学数据
| 目录号 | A10725 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 523.5 |
| Formula | C28H32F2N2O.2HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 67469-78-7 |
| Synonyms | GBR12909 |
| SMILES | C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
溶解度
| In vitro | DMSO | 15 mg/mL (28.65 mM) |
| Water | 4 mg/mL (7.64 mM) |
| Ethanol | 2 mg/mL (3.82 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 19.1 mL | 95.51 mL | 191.02 mL |
| 0.5 mM | 3.82 mL | 19.1 mL | 38.2 mL |
| 1 mM | 1.91 mL | 9.55 mL | 19.1 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.82 mL |
*The above data is based on the productmolecular weight 523.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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