生物活性
Moxifloxacin HCl是一种喹诺酮/氟喹诺酮类抗菌剂。
靶点信息
| Topoisomerase II | Topoisomerase IV | | | |
| | | | |
化学数据
| 目录号 | A10609 |
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 437.9 |
| Formula | C21H24FN3O4.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 186826-86-8 |
| Synonyms | Avelox, Avalox, BAY 12-8039 |
| SMILES | COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl |
溶解度
| In vitro (25°C) | DMSO | 77 mg/mL (175.84 mM) |
| Water | 53 mg/mL (121.03 mM) |
| Ethanol | Insoluble |
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 22.84 mL | 114.18 mL | 228.36 mL |
| 0.5 mM | 4.57 mL | 22.84 mL | 45.67 mL |
| 1 mM | 2.28 mL | 11.42 mL | 22.84 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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