ROCK-IN-1是一种有效的ROCK抑制剂，能够抑制ROCK2的活性，IC50值为1.2nM。
CAS：934387-35-6
分子式：C20H18FN3O
分子量：335.37
纯度：98%
存储：Store at -20°C

Background:

ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.

ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].

[1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6.