PSB-1115 is an antagonist of the adenosine A2B receptor (Ki = 53.4 nM).
CAS：409344-71-4
分子式：C14H13N4O5S.K
分子量：388.4
纯度：98%
存储：Store at -20°C

Background:

PSB-1115 is an antagonist of the adenosine A2B receptor (Ki = 53.4 nM). It is selective for A2B over A1 and A2A receptors, which have Ki values of 2,200 and 24,000 nM, respectively, and over the A3 receptor, which it inhibits only 14% at a concentration of 10 µM. PSB-1115 pre-treatment reduces relaxation of rat trachea induced by repeated dosing of the non-selective adenosine agonist NECA .