生物活性
Carboplatin是一种化学疗法药物，可用于治疗某些形式的癌症（主要是卵巢癌，肺癌，头颈癌）。顺铂和卡铂以及奥沙利铂与DNA相互作用，类似于烷基化剂的作用机理。
靶点信息
| DNA synthesis (A2780, SKOV-3, IGROV-1, HX62 cells) | | | | |
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化学数据
| 目录号 | A10182 |
| M. Wt | 371.3 |
| Formula | C6H12N2O4Pt |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 41575-94-4 |
| Synonyms | Paraplatin |
| SMILES | C1CC(C1)(C(=O)O)C(=O)O.N.N.[Pt] |
溶解度
| In vitro | DMSO | Insoluble |
| Water | Warmed: 14 mg/mL (37.71 mM) |
| Ethanol | Insoluble |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 26.93 mL | 134.66 mL | 269.32 mL |
| 0.5 mM | 5.39 mL | 26.93 mL | 53.86 mL |
| 1 mM | 2.69 mL | 13.47 mL | 26.93 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
*The above data is based on the productmolecular weight 371.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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