生物活性
Candesartan Cilexetil一种特异性的，非肽类血管生成素II受体（ATR）拮抗剂，也是Candesartan的前体药物，是ATR拮抗剂
靶点信息
化学数据
| 目录号 | A10176 |
| M. Wt | 610.7 |
| Formula | C33H34N6O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 145040-37-5 |
| Synonyms | Atacand, Amias, Blopress, Ratacand, TCV 116, TCY 116 |
| SMILES | CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6 |
溶解度
| In vitro | DMSO | 113 mg/mL (185.04 mM) |
| Water | Insoluble |
| Ethanol | 4 mg/mL (6.55 mM) |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 16.37 mL | 81.87 mL | 163.75 mL |
| 0.5 mM | 3.27 mL | 16.37 mL | 32.75 mL |
| 1 mM | 1.64 mL | 8.19 mL | 16.37 mL |
| 5 mM | 0.33 mL | 1.64 mL | 3.27 mL |
*The above data is based on the productmolecular weight 610.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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