CaMKII-IN-1是CaMKII高效选择性抑制剂，IC50值为63nM,对CaMKIV, MLCK, p38a, Akt1,和PKC几乎无作用。
CAS：1208123-85-6
分子式：C29H30ClN5O2S
分子量：548.1
纯度：98%
存储：Store at -20°C

Background:

CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor with IC50 of 63 nM; significantly high selectivity against CaMKIV, MLCK, p38a, Akt1, and PKC.IC50 value: 63 nMTarget: CaMKII

[1]. Asano S, et al. 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6696-8.