TBK1/IKKε-IN-5 (compound 1) 是 TBK1 和 IKKε 的双抑制剂，其 IC50 值分别为 1 nM 和 5.6 nM。
CAS：1893397-65-3
分子式：C28H31N7O3
分子量：513.59
纯度：98%
存储：Store at -20°C

Background:

TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively[1]. IC50: 1 nM (TBK1), 5.6 nM (IKKε)[1].

[1]. Jenkins RW, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 Feb;8(2):196-215.