p38MAPK-IN-1是p38MAPK新型高效选择性抑制剂,IC50值68nM。
CAS：1006378-90-0
分子式：C21H15F2N2O
分子量：349.35
纯度：98%
存储：Store at -20°C

Background:

p38 MAPK-IN-1 is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM, shows sustained levels, low clearance and good bioavailability.

[1]. Lumeras W, et al. 1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase. J Med Chem. 2011 Nov 24;54(22):7899-910.