Mcl1-IN-1 是一种骨髓细胞因子 1 (Mcl-1) 抑制剂，IC50 为 2.4 ?M。
CAS：713492-66-1
分子式：C23H18ClN3O4
分子量：435.86
纯度：98%
存储：Store at -20°C

Background:

Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 (Mcl-1) (IC50=2.4 µM). Mcl-1|2.4 μM (IC50)

Mcl1-IN-1 (Compound 1) is a Mcl-1 inhibitor, which demonstrates good Mcl-1 inhibition (IC50=2.4 µM) with no appreciable inhibition of Bcl-xL at 100 µM[1].

[1]. Richard DJ, et al. Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9.