Draflazine (R-75231) 是一种 ENT1 抑制剂。Draflazine (R-75231) 在 CFA 机械痛觉过敏模型，热力学和机械痛觉过敏的卡拉胶炎症模型中完全逆转了超敏反应。
CAS：120770-34-5
分子式：C30H33Cl2F2N5O2
分子量：604.52
纯度：98%
存储：Store at -20°C

Background:

Draflazine (R-75231) is a ENT1 inhibitor. Draflazine (R-75231) completely reverses the hypersensitivity in the complete Freund’s adjuvant (CFA) model of mechanical hyperalgesia and the carrageenan inflammation model of thermal and mechanical hyperalgesia[1]. ENT1[1]

[1]. Maes SS, et al. Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs. J Pain Res. 2012;5:391-400.