USP7-IN-1 是一种选择性的，可逆的泛素蛋白特异性蛋白酶 (USP7) 抑制剂，IC50 值为 77 μM，可用于癌症研究。
CAS：1381291-36-6
分子式：C23H24ClN3O3
分子量：425.91
纯度：98%
存储：Store at -20°C

Background:

USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]

USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].

[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1