c-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of<200 nm.
CAS：1225278-16-9
分子式：C26H21F2N5O3
分子量：489.47
纯度：98%
存储：Store at -20°C

Background:

c-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of<200 nM.

c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of<200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR α and β with IC50s of<2 uM,<10 uM and<10 uM, respectively[1].

参考文献:
[1]. Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1