Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.
CAS：954126-98-8
分子式：C19H21ClFN3O4S
分子量：441.9
纯度：98%
存储：Store at -20°C

Background:

Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.

Danirixin is a small molecule, CXCR2 antagonist being evaluated as a potential anti-inflammatory medicine[1].

参考文献:
[1]. Miller BE, et al. The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)--a selective CXCR2 antagonist--in healthy adult subjects. BMC Pharmacol Toxicol. 2015 Jun 20;16:18.