Mutated EGFR-IN-1是突变型EGFR（L858R EGFR，Exonl9缺失活化突变和T790M抗性突变）抑制剂的中间体。
CAS：1421372-66-8
分子式：C25H31N7O
分子量：445.56
纯度：98%
存储：Store at -20°C

Background:

Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant and T790M resistance mutant.IC50 value:Target: Mutated EGFR inhibitorMore information can be found in Patent WO 2013014448 A1.2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer. EGFRL858R EGFRExon 19 deletion/T790M EGFRT790M

[1]. Patent WO 2013014448 A1. 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer.