Iclaprim是一种新的,有选择性的细菌二氢叶酸抑制剂,可以抑制金黄色葡萄球菌(MRSA)的生长,其MIC90值为0.06μg/mL。
CAS：192314-93-5
分子式：C19H22N4O3
分子量：354.4
纯度：98%
存储：Store at -20°C

Background:

Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL.

Iclaprim inhibits the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL[2].

[1]. Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21. [2]. Kohlhoff SA, et al. Iclaprim. Expert Opin Investig Drugs. 2007 Sep;16(9):1441-8.