BIBF0775是有效，选择性的TGFβI型受体(Alk5)的抑制剂，IC50为34nM。
CAS：334951-90-5
分子式：C31H34N4O2
分子量：494.63
纯度：98%
存储：Store at -20°C

Background:

BIBF0775 is a potent and selective transforming growth factor β (TGFβ) type I receptor (Alk5) inhibitor with an IC50 of 34 nM. IC50: 34 nM (Alk5)[1]

[1]. Roth GJ, et al. Design, synthesis, and evaluation of indolinones as inhibitors of the transforming growth factor β receptor I (TGFβRI). J Med Chem. 2010 Oct 28;53(20):7287-95.