DC41是一种DC1衍生物。DC1，CC-1065 的简化类似物，是用于靶向治疗癌症的细胞毒性 DNA 烷基化酶的抗体偶联物。
CAS：1354787-69-1
分子式：C37H34ClN5O4S
分子量：680.21
纯度：98%
存储：Store at -20°C

Background:

DC41 is a DC1 derivative. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer[1][2].

[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82. [2]. Kovtun YV, et al. Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen. Cancer Res. 2006 Mar 15;66(6):3214-21.