ONO8430506(ONO-8430506) is a novel and potent autotaxin inhibitor that enhances the antitumor effect of paclitaxel in a breast cancer model. Lysophosphatidic acid (LPA) is a bioactive lipid mediator that elicits a number of biological functions, including smooth muscle contraction, cell motility, proliferation, and morphological change. LPA is endogenously produced by autotaxin (ATX) from extracellular lysophosphatidylcholine (LPC) in plasma.

纯度：≥98%

CAS：1354805-08-5