Anle138b is a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.. Anle138b blocks the activity of conducting Aβ pores without changing the membrane embedded Aβ-oligomer structure, at the mechanistic level. Anle138b blocks interpeptide main chain interactions and impedes the spontaneous formation of ordered β-sheet structures, in particular those with out-of-register antiparallel β-strands.

纯度：≥98%

CAS：882697-00-9