TY-51469 is a Chymase inhibitor TY-51469 in therapy of inflammatory bowel disease. TY-51469 showed IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively. TY-51469 might ameliorate the progression of DSS-induced colitis possibly by increasing the expression of Tregs and cytokines.

纯度：≥98%

CAS：603987-59-3