Thapsigargin is a novel and potent non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) and an Endoplasmic Reticulum (ER) stress inducing agent. It is a potent, cell-permeable, IP3-independent intracellular calcium releaser, that works by blocking the transient increase in intracellular Ca2+ induced by angiostatin and endostatin, and inducing apoptosis by disrupting intracellular free Ca2+ levels.

纯度：≥98%

CAS：67526-95-8