| CAS NO: | 6429-04-5 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5g | 电议 |
| 10g | 电议 |
| 25g | 电议 |
| 50g | 电议 |
| Molecular Weight (MW) | 379.88 |
|---|---|
| Formula | C20H25NO4.HCl |
| CAS No. | 6429-04-5 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 76 mg/mL (200.1 mM) |
| Water: <1 mg/mL | |
| Ethanol: 7 mg/mL (18.4 mM) | |
| SMILES Code | COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl |
| Synonyms | Norlaudanosine HCl; Tetrahydropapaverine |
| In Vitro | In vitro activity: Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons. Tetrahydropapaverine inhibits serotonin biosynthesis in serotonin-producing murine mastocytoma P815 cells with an IC50 of 7.5 μM and reduces tryptophan hydroxylase activity with an IC50 of 5.7 μM. |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Life Sci. 2004 Sep 3;75(16):1949-57; Brain Res. 1997 Apr 18;754(1-2):260-8. |
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