| CAS NO: | 651-06-9 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 500mg | 电议 |
| 1g | 电议 |
| 5g | 电议 |
| 10g | 电议 |
| 25g | 电议 |
| 50g | 电议 |
| Molecular Weight (MW) | 280.3 |
|---|---|
| Formula | C11H12N4O3S |
| CAS No. | 651-06-9 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 56 mg/mL (199.8 mM) |
| Water: <1 mg/mL | |
| Ethanol: <1 mg/mL | |
| Other info | Chemical Name: 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide InChi Key: GPTONYMQFTZPKC-UHFFFAOYSA-N InChi Code: InChI=1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15) SMILES Code: O=S(C1=CC=C(N)C=C1)(NC2=NC=C(OC)C=N2)=O |
| Synonyms | NSC-683528; Sulfameter; I-2586; I 2586; NSC683528; I2586; SH 613; Sulfametoxipirimidine; Solfametossidiazina [DCIT]; NSC 683528; |
| In Vitro | In vitro activity: Sulfameter(Bayrena) is a long-acting sulfonamide antibacterial. It is used as a leprostatic agent in the treatment of urinary tract infections. Six physically healthy patients each were given 2 g of sulfameter simultaneously with a high lipid, high protein and high carbohydrate test meal. This experiment was designed as a threefold crossover study, and there was a randomized assignment of patients to the different conditions. The results show that sulfameter is significantly better absorbed when administered with a high lipid meal than when given with a high protein or high carbohydrate meal, demonstrated by the areas under the serum concentration curves (AUC), by the peak serum concentration and by the cumulative renal excretion. |
|---|---|
| In Vivo | |
| Animal model | |
| Formulation & Dosage | |
| References | Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):260-3; Clin Pharmacol Ther. 1969 Jul-Aug;10(4):591-4. |
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