Ciproxifan (formerly known as FUB-359) is a highly potent and selective histamine H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. In addition, Ciproxifan has been reported to competitively antagonize the (R) α-MeHA induced relaxation of electrically stimulated guinea pig ileum longitudinal muscle. Besides, Ciproxifan has been revealed to have the effect on [125I]iodoproxyfan binding with a Ki value of 0.7±0.2 nM.

纯度：≥98%

CAS：184025-19-2