PK68 is a novel, potent and selective type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, exhibiting inhibition of RIPK1-dependent necroptosis. PK68 significantly ameliorates TNF-induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis.

纯度：≥98%

CAS：2173556-69-7