A-484954 (A484954; A 484954) is a highly selective, cell-permeable and ATP-competitive eukaryotic elongation factor-2 (eEF2) inhibitor with potential antitumor activity. It inhibits eEF2 with an IC50 of 280 nM. eEF2 is a member of the GTP-binding translation elongation factor family, and an essential factor for protein synthesis and cell survival.

纯度：≥98%

CAS：142557-61-7