Description:JAK-IN-4 is a novel and potent JAK inhibitor with immuomodulatory activity, and may be used for arthritis. It inhibits JAK3, JAK1, TYK2 and JAK2 with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM, respectively.

References: Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Med Chem Lett. 2019 Feb 13;10(3):306-311.

纯度：≥98%

CAS：1400877-37-3