FGH10019 is a novel and potent inhibitor of the sterol regulatory element-binding protein (SREBP) with IC50 of 1 μM. It has high aqueous solubility and membrane permeability and may serve as a seed molecule for further development. Treatment of the CHO-K1 cells with analog FGH10019 decreases the percentage of the mature form of SREBP-2 (68 kDa) at lower concentrations than treatment with fatostatin.

纯度：≥98%

CAS：1046045-61-7