Danuglipron (PF-06882961; PF06882961) is a novel, non-peptide, allosteric and orally bioavailable agonist of the glucagon-like peptide-1 receptor (GLP-1R). It exhibited comparable efficacy to injectable peptidic GLP-1R agonists in a humanized mouse model. Agonism of the glucagon-like peptide-1 receptor (GLP-1R) results in glycemic lowering and body weight loss and is a therapeutic strategy to treat type 2 diabetes (T2D) and obesity.

纯度：≥98%

CAS：2230198-02-2