N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

2107273-50-5

C47H67ClN2O10

855.5

n-methyl-n-methyl-o-m-peg4-o-propargyl-peg4-cy5;N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years