| CAS NO: | 1422365-94-3 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
IM156 (also known as HL-156A) is a metformin derivative thac acts as a novel and highly potent AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model. References: [1].Row
H, et al. HL271, a novel chemical compound derived from metformin,
differs from metformin in its effects on the circadian clock and
metabolism. Biochem Biophys Res Commun. 2016 Jan 15;469(3):783-9. [2].Bang
E, et al. The Improving Effect of HL271, a Chemical Derivative of
Metformin, a Popular Drug for Type II Diabetes Mellitus, on
Aging-induced Cognitive Decline. Exp Neurobiol. 2018 Feb;27(1):45-56. [3].Sun
Young Rha, et al. Phase I study of IM156, a novel potent biguanide
oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced
solid tumors. Journal of Clinical Oncology 38(15_suppl):3590-3590. Related CAS #:1422365-94-3 (acetate)
1422365-93-2 (free base) 1422365-52-3 (HCl)
2043654-64-2 (TFA)
2043654-70-0 (malonate)
2043654-72-2 (furmate)
2043654-97-1 (tosylate)
2043654-98-2 (mesylate)
纯度：≥98%
CAS：1422365-94-3
m.cnreagent.com