MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd : 2.0 μM , IC50 : 4 μM).

When Eya2 ED is dialyzed into 10 μM EDTA to remove Mg2+, it binds MLS000544460 with a higher affinity (Kd=0.80 μM), indicating that this class of compounds does not require Mg2+ for its interaction with the Eya2 ED[1].

352336-36-8

C17H12FN3O2S

341.36

MLS000544460

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years