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CAY10760
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10760图片
CAS NO:391889-85-3
包装与价格:
包装价格(元)
25 mg电议
50 mg电议

产品介绍

产品描述

CAY10760 is an inhibitor of the protein-protein interaction between RAD51 recombinase and BRCA2 (EC50= 19 μM in a cell-free competitive ELISA).1It decreases homologous recombination by 54% in wild-typeBRCA2-expressing BxPC-3 pancreatic cancer cells when used at a concentration of 20 μM. CAY10760 (20 μM) decreases proliferation of BxPC-3, as well as mutantBRCA2-expressing Capan-1, cancer cells when used alone or in combination with the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib .

Cas No.

391889-85-3

分子式

C28H24ClN3O3

分子量

485.96

储存和溶解度

DMF:PBS (pH 7.2) (1:2):0.3 mg/mL
DMF:11 mg/mL
DMSO:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years