OSMI-1 (OSMI1; OSMI 1) is a novel, potent, cell permeable and quinolinone-6-sulfonamide-based inhibitor of O-GlcNAc transferase (OGT) with an IC50 value of 2.7 μM. OSMI-1 induces a mass shift of nucleoporin62 (Nup62) that corresponds to the loss of O-GlcNAc residues and decreases levels of cellular O-GlcNAcase.

纯度：≥98%

CAS：1681056-61-0