Thio-ITP (6-Thioinosine 5′-triphosphate) is an RNA polymerase activity competitive inhibitor. Thio-ITP has a high apparent affinity for the polymerases (RNA polymerase I K i : 40.9 μM; RNA polymerase II K i : 38.0 μM).

Thio-ITP inhibits both endogenous and exogenous DNA-directed RNA synthesis[1].

27652-34-2

C10H15N4O13P3S

524.23

6-Thio-ITP;Thio-ITP;6-Thioinosine 5′-triphosphate;6-Mercaptopurine-riboside-5'-triphosphate

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years