KIRA-7 (KIRA7) is an imidazopyrazine-based anti-fibrotic compound acting as an IRE1α kinase/Rnase inhibitor with the potential to be used in fibrosis. It allosterically inhibits IRE1α kinase with an IC50 of 0.11/0.22 uM. It is able to reverse bleomycin-induced fibrosis when given 2 weeks after bleomycin exposure in vivo.

纯度：≥98%

CAS：1937235-76-1