DCZ0415 (DCZ-0415; DCZ 0415) is a novel and highly potent TRIP13 inhibitor that is able to impair nonhomologous end joining repair and inhibits NF-κB activity. DCZ0415 induces anti-myeloma activity in vitro, in vivo, and in primary cells derived from drug-resistant myeloma patients.

References:A Small Molecule Inhibitor Targeting TRIP13 suppresses multiple myeloma progression. Cancer Res. 2019 Nov 15. pii: canres.3987.2018.

纯度：≥98%

CAS：2242470-43-3