Pulrodemstat besylate (formerly CC-90011 besylate; LSD1-IN-7), the besylate salt of CC-90011 (LSD1-IN7; CC90011), is a highly potent and orally bioavailable inhibitor of lysine specific demethylase-1 (LSD1) with potential anticancer activity. CC-90011 exhibits potent on-target induction of cellular differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cell lines, and antitumor efficacy in patient-derived xenograft (PDX) SCLC models. CC-90011 is currently in phase 2 trials in patients with first line, extensive stage SCLC (ClinicalTrials.gov identifier: NCT03850067).

纯度：≥98%

CAS：2097523-60-7