HKI-357 (HKI357) is a novel and potent dual inhibitor of EGFR and ERBB2 that irreversibly inhibits EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation.

纯度：≥98%

CAS：848133-17-5