Valsartan Ethyl Ester is a major impurity of Valsartan. Valsartan (also known as CGP-48933), an approved antihypertensive drug, is a potent and selective angiotensin II receptor antagonist that is used for the treatment of high blood pressure and congestive heart failure. Valsartan is selective for the type I (AT1) angiotensin receptor. Valsartan dose-dependently inhibits the vasoconstriction induced by angiotensin II and lowers blood pressure in renin-dependent models of hypertension.

References: [1]. Shan H, et al. Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity. J Cell Mol Med. 2014 Jun;18(6):1071-80.

纯度：≥98%

CAS：1111177-30-0