GNE 2861 是一种 PAK 抑制剂，具有 II 组的选择性。它抑制 PAK4、PAK5 和 PAK6 的IC50值分别为7.5、36和126 nM。

GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.

GNE 2861 is compound 4 in the reference.

1394121-05-1

C22H26N6O2

406.48

DMSO:99 mg/mL (243.55 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years