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Naratriptan HCl(GR-85548A HCl)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Naratriptan HCl(GR-85548A HCl)图片
CAS NO:143388-64-1
规格:≥98%
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议
1g电议
2g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)371.93
FormulaC17H25N3O2S.HCl
CAS No.143388-64-1
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 74 mg/mL (199.0 mM)
Water: 22 mg/mL (59.2 mM)
Ethanol: <1 mg/mL
Other info

Chemical Name: N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide hydrochloride

InChi Key: AWEZYKMQFAUBTD-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H

SMILES Code: CN1CCC(C2=CNC3=C2C=C(CCS(=O)(NC)=O)C=C3)CC1.[H]Cl

SynonymsGR-85548A; Naratriptan HCl; Naratriptan Hydrochloride; GR 85548A; GR85548A; Amerge; Naramig;
实验参考方法
In Vitro

In vitro activity: Naratriptan is a triptan drug marketed by GlaxoSmithKline and is used for the treatment of migraine headaches. Naratriptan is available in 2.5 mg tablets. It is a selective 5-HT1 receptor subtype agonist. Naratriptan is used for the treatment of the acute migraine attacks and the symptoms of migraine, including severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound or light.

In Vivo
Animal model
Formulation & Dosage
References

Cephalalgia. 1997 May;17(3):145-52.