| CAS NO: | 83861-02-3 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| Cas No. | 83861-02-3 |
| Canonical SMILES | OC([C@H](CC1=CC=CC=C1)N[C@H](C(NCCC(O)=O)=O)CC2=CC=CC=C2)=O |
| 分子式 | C21H24N2O5 |
| 分子量 | 384.43 |
| 溶解度 | DMSO: 125 mg/mL (325.16 mM) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | SCH 32615 is an enkephalinase (the enzymes responsible for the degradation of endogenous enkephalins) inhibitor. SCH 32615 can enhance surgery- and pregnancy-induced analgesia in mice[1][2]. SCH 32615 blocks the degradation of Met5-enkephalin by isolated enkephalinase, with the Ki of 19.5 nM[3]. SCH 32615 (150 mg/kg; s.c.) enhances surgery activated endogenous analgesia in mice[1]. [1]. Jayaram A, et, al. An enkephalinase inhibitor, SCH 32615, augments analgesia induced by surgery in mice. Anesthesiology. 1995 May;82(5):1283-7. [2]. Jayaram A, et, al. SCH 32615, an enkephalinase inhibitor, enhances pregnancy-induced analgesia in mice. Anesth Analg. 1995 May;80(5):944-8. [3]. Chipkin RE, et, al. Pharmacology of SCH 34826, an orally active enkephalinase inhibitor analgesic. J Pharmacol Exp Ther. 1988 Jun;245(3):829-38. |
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