hGGPPS-IN-1 (Compound 18b) is a potent inhibitor of the human geranylgeranyl pyrophosphate synthase (hGGPPS). hGGPPS-IN-1 is an analogue of C-2-substituted thienopyrimidine-based bisphosphonates (C2-ThP-BPs). hGGPPS-IN-1 induces target-selectiveapoptosisof multiple myeloma (MM) cells and exhibits antimyeloma activity in vivo^[1].

401.27

C₁₃H₁₃N₃O₆P₂S

1429012-38-3

Room temperature in continental US; may vary elsewhere.

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