Dutogliptin tartrate (PHX-1149) is an orally available, potent, and selectivedipeptidyl peptidase-4(DPP4) inhibitor for the treatment of type 2 diabetes mellitus.

DPP4^[1]

Dutogliptin exhibits low plasma protein binding (11%) and is rapidly absorbed with a T_maxof 3-4 h and a half-life of 10-13 h. Dutogliptin is metabolically stable and does not inhibit or induce the activity of major CYP450s^[2].

391.18

C₁₄H₂₆BN₃O₉

890402-81-0

杜拓格利普汀酒石酸盐

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.